منابع مشابه
Blindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملEvaluation of randomized controlled trials.
Although randomized controlled trials (RCTs) play a key role in modern medicine, considerable variability exists in their quality and in the reliability (reproducibility) of their results. The present article discusses features that characterize high-quality trials, such as intent-to-treat (ITT) analysis, the avoidance of patient exclusions, and a procedure for evaluating the reliability of stu...
متن کاملblindness in randomized controlled trials
in combination with randomization, blinding or masking is an important factor in randomized controlled trials (rcts), particularly in trials that assess therapeutic effects. here an attempt is made to explain blindness and why it is important. in clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملEvaluation of randomized controlled trials on complementary and alternative medicine.
OBJECTIVES Use of complementary and alternative medicine (CAM) is growing in all Western countries. The goal of this study was to evaluate quality of randomized controlled trials (RCTs) of CAM interventions for specific diagnoses to inform clinical decision making. METHODS MEDLINE and related databases were searched for CAM RCTs. Visual review was done of bibliographies, meta-analyses, and CA...
متن کاملRandomized Controlled Trials
This paper covers the topic of randomized controlled trials in social, educational, criminological, health, and other human service sectors. It is studded with illustrations from developed and developing countries. We address the basic ideas that underlie trials in different ways, and cover contemporary definitions and vernacular, some history, and idea of cumulating evidence from such trials i...
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ژورنال
عنوان ژورنال: Circulation
سال: 2007
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.106.618603